Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30910160 | 1.00 | BRD4 (0.43) | BRD4RORCLMNATSHRKDM4E | |
| SCHEMBL30910074 | 0.84 | GAA (0.43) | BRD4LMNATSHRKDM4EALDH1A1 | |
| SCHEMBL26088646 | 0.84 | GAA (0.43) | BRD4LMNATSHRKDM4EALDH1A1 | |
| SCHEMBL30379039 | 0.83 | BRD4 (0.47) | BRD4LMNATSHRKDM4EALDH1A1 | |
| SCHEMBL29220789 | 0.83 | BRD4 (0.47) | BRD4LMNATSHRKDM4EALDH1A1 | |
| SCHEMBL26089531 | 0.83 | GAA (0.43) | BRD4LMNATSHRKDM4EALDH1A1 | |
| SCHEMBL30379654 | 0.83 | GAA (0.43) | BRD4LMNATSHRKDM4EALDH1A1 | |
| SCHEMBL26089031 | 0.82 | SIGMAR1 (0.46) | BRD4LMNATSHRKDM4EALDH1A1 | |
| SCHEMBL30378990 | 0.82 | SIGMAR1 (0.46) | BRD4LMNATSHRKDM4EALDH1A1 | |
| SCHEMBL30910129 | 0.81 | BRD4 (0.43) | BRD4TSHRALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118119612-A | Novel compounds and pharmaceutical compositions comprising the same | 萨皮恩斯生物有限公司 | 2024-05-31 | — | — | CN | disclosed |