Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.60 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.52 |
| ▸ | HTR7 | P34969 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.43 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29221075 | 0.89 | PTPN1 (0.54) | PTPN1RIPK1HTR7KDM4EALDH1A1 | |
| SCHEMBL5429419 | 0.85 | PTPN1 (0.61) | PTPN1HTR7KDM4ECAMK2DNPC1 | |
| SCHEMBL29221029 | 0.84 | RIPK1 (0.51) | PTPN1RIPK1HTR7KDM4EALDH1A1 | |
| SCHEMBL29221006 | 0.84 | RIPK1 (0.51) | PTPN1RIPK1HTR7KDM4EALDH1A1 | |
| SCHEMBL30283716 | 0.84 | PTPN1 (0.46) | PTPN1RIPK1KDM4EALDH1A1NR1H4 | |
| SCHEMBL5424136 | 0.84 | PTPN1 (0.53) | PTPN1HTR7KDM4EALDH1A1THRB | |
| SCHEMBL29221058 | 0.83 | PTPN1 (0.60) | PTPN1RIPK1HTR7CSNK2A2CSNK2B | |
| SCHEMBL29221087 | 0.82 | PTPN1 (0.56) | PTPN1HTR7KDM4EALDH1A1HPGD | |
| SCHEMBL29221014 | 0.82 | PTPN1 (0.61) | PTPN1RIPK1HTR7PPARG | |
| SCHEMBL29221042 | 0.82 | PTPN1 (0.58) | PTPN1RIPK1HTR7KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084889-B | Indole 3-aryl-5-carboxamide derivative and application thereof | 宁夏医科大学 | 2024-09-27 | — | — | CN | disclosed |
| CN-118084889-A | Indole 3-aryl-5-carboxamide derivative and application thereof | 宁夏医科大学 | 2024-05-28 | — | — | CN | disclosed |