SCHEMBL2922286

SCHEMBL2922286

CC(O[N+](=O)[O-])C(CCCO)O[N+](=O)[O-]

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.35
PTPN1 P18031 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3064346 1.00 GSR (0.35) GSRPTPN1
SCHEMBL17765362 0.95 GSR (0.31) GSRPTPN1
SCHEMBL17765361 0.95 GSR (0.31) GSRPTPN1
SCHEMBL12374861 0.83 LMNA (0.38)
SCHEMBL12009607 0.83 LMNA (0.38)
SCHEMBL12009606 0.83 LMNA (0.38)
SCHEMBL12753933 0.83 LMNA (0.38)
SCHEMBL2762644 0.81 LMNA (0.34)
SCHEMBL12753953 0.79
SCHEMBL10158047 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2225225-A2 ANGIOTENSIN II RECEPTOR ANTAGONISTS Merck Sharp & Dohme Corp. (US) 2010-09-08 EP disclosed
WO-2009070241-A2 ANGIOTENSIN II RECEPTOR ANTAGONISTS MERCK & CO., INC. (US) 2009-06-04 WO disclosed