SCHEMBL29222969

SCHEMBL29222969

N#Cc1cccc(-c2ccc(=O)n(Cc3cccc(-c4ncc(OCC5CCN(CCCCCC(=O)O)CC5)cn4)c3)n2)c1

nearest known ligand 0.76

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ MET P08581 18/20 0.76
▸ NQO2 P16083 1/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29223038 0.97 MET (0.78) METNQO2
SCHEMBL31690421 0.94 MET (0.80) METNQO2
SCHEMBL30905900 0.90 MET (0.73) METNQO2
SCHEMBL29223103 0.90 MET (0.80) METNQO2
SCHEMBL31690377 0.90 MET (0.80) METNQO2
SCHEMBL30905864 0.90 MET (0.83) METNQO2
SCHEMBL30905826 0.88 MET (0.74) METNQO2
SCHEMBL29223027 0.88 MET (0.83) METNQO2
SCHEMBL2480684 0.87 MET (0.82) METNQO2
SCHEMBL2458256 0.87 MET (0.83) METNQO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118084871-B Compound for targeted degradation of c-Met protein and preparation method and application thereof 中国药科大学 2024-07-09 — — CN disclosed
CN-118084871-A Compound for targeted degradation of c-Met protein and preparation method and application thereof 中国药科大学 2024-05-28 — — CN disclosed
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