Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 18/20 | 0.63 |
| ▸ | DDB1 | Q16531 | 17/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23301622 | 0.86 | CRBN (0.67) | CRBNDDB1POLB | |
| SCHEMBL24206650 | 0.86 | CRBN (0.67) | CRBNDDB1POLB | |
| SCHEMBL25187964 | 0.86 | CRBN (0.67) | CRBNDDB1POLB | |
| SCHEMBL31232850 | 0.85 | CRBN (0.63) | CRBNDDB1POLB | |
| SCHEMBL30830879 | 0.84 | CRBN (0.68) | CRBNDDB1POLB | |
| SCHEMBL24880998 | 0.83 | CRBN (0.61) | CRBNDDB1POLBRORC | |
| SCHEMBL29223447 | 0.82 | CRBN (0.62) | CRBNDDB1POLB | |
| SCHEMBL31232880 | 0.82 | CRBN (0.64) | CRBNDDB1POLB | |
| SCHEMBL21876964 | 0.82 | DDB1 (0.67) | CRBNDDB1 | |
| SCHEMBL23301226 | 0.82 | DDB1 (0.67) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858874-A | HPK1 degrading agents, compositions comprising the same, and methods of use thereof | 百放开曼有限公司 | 2024-04-09 | — | — | CN | disclosed |