SCHEMBL29224820

SCHEMBL29224820

COc1ccc(C2(O)C(=O)c3ccc(O)cc3OC2O)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIT P10721 1/20 0.46
MAOB P27338 2/20 0.44
CYP19A1 P11511 4/20 0.43
PTGS2 P35354 2/20 0.41
ESR1 P03372 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA4 P22748 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
TYR P14679 1/20 0.39
CBS P35520 1/20 0.39
PTPN1 P18031 3/20 0.38
CYP3A4 P08684 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.38
THRB P10828 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29099783 0.77 PTPN1 (0.53) KITMAOBCYP19A1PTGS2ESR1
SCHEMBL26982934 0.70 SMN1; SMN2 (0.63) CYP19A1ESR1CBSCYP3A4MEN1
SCHEMBL4804016 0.70 ESR1 (0.58) KITMAOBCYP19A1ESR1CBS
SCHEMBL28557922 0.70 MAOB (0.46) KITMAOBCYP19A1PTGS2ESR1
SCHEMBL30641816 0.69 CYP19A1 (0.58) MAOBCYP19A1CA1CA2CA4
SCHEMBL38664154 0.68 CYP19A1 (0.40) MAOBCYP19A1ESR1PTPN1CYP3A4
SCHEMBL31028354 0.68 CYP19A1 (0.86) MAOBCYP19A1PTPN1CYP3A4MAPT
SCHEMBL7195893 0.68 CYP19A1 (0.86) MAOBCYP19A1PTPN1CYP3A4MAPT
(3R)-4'-Methoxy-2',3',7-Trihydroxyisoflavanone SCHEMBL572272 0.68 PTPN1 (0.61) KITMAOBCYP19A1CA1CA2
(3R)-4'-Methoxy-2',3',7-Trihydroxyisoflavanone SCHEMBL17963716 0.68 PTPN1 (0.61) KITMAOBCYP19A1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117813017-A Method for improving intestinal microbiota diversity 雀巢产品有限公司 2024-04-02 CN disclosed