Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.50 |
| ▸ | CBS | P35520 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4725052 | 0.92 | CYP19A1 (0.59) | ESR1ESR2CYP19A1CBSMAPT | |
| SCHEMBL571732 | 0.88 | ESR2 (0.73) | ESR1ESR2CYP19A1MAOBPTPN1 | |
| SCHEMBL2029052 | 0.88 | ESR2 (0.73) | ESR1ESR2CYP19A1MAOBPTPN1 | |
| SCHEMBL30555701 | 0.88 | ESR2 (0.73) | ESR1ESR2CYP19A1MAOBPTPN1 | |
| SCHEMBL11396242 | 0.85 | ESR1 (0.55) | ESR1ESR2CYP19A1CBSMEN1 | |
| SCHEMBL26982934 | 0.82 | SMN1; SMN2 (0.63) | ESR1ESR2CYP19A1CBSMEN1 | |
| SCHEMBL4799817 | 0.81 | POLB (0.68) | CYP19A1CBSMEN1POLBMAPT | |
| SCHEMBL2069507 | 0.75 | ALOX12 (0.74) | CYP19A1MEN1POLBMAPTKMT2A | |
| SCHEMBL29559241 | 0.75 | ALOX12 (0.74) | CYP19A1MEN1POLBMAPTKMT2A | |
| SCHEMBL14045015 | 0.75 | ESR1 (0.71) | ESR1ESR2CYP19A1MAOBPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070050865-A1 | Polynucleotide encoding 2-hydorxyisoflavanone dehydratase and application of the same | NIHON UNIVERSITY (JP) | 2007-03-01 | — | — | US | claimed |
| US-8809627-B2 | Plant isoflavone and isoflavanone O-methyltransferase genes | THE SAMUEL ROBERTS NOBLE FOUNDATION, INC. (US) | 2014-08-19 | — | — | US | disclosed |
| US-20080317880-A1 | PLANT ISOFLAVONE AND ISOFLAVANONE O-METHYLTRANSFERASE GENES | THE SAMUEL ROBERTS NOBLE FOUNDATION | 2008-12-25 | — | — | US | disclosed |
| US-7462478-B2 | isolated from licorice; catalyzes a dehydration reaction of 2-hydroxy hisoflavanone | NIHON UNIVERSITY (JP) | 2008-12-09 | — | — | US | disclosed |
| US-20070050865-A1 | Polynucleotide encoding 2-hydorxyisoflavanone dehydratase and application of the same | NIHON UNIVERSITY (JP) | 2007-03-01 | — | — | US | disclosed |