Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 6/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.46 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17145402 | 0.81 | PLK1 (0.55) | RAF1SIRT2SIRT1SIRT3MKNK1 | |
| SCHEMBL28284702 | 0.81 | SIRT2 (0.54) | RAF1SIRT2SIRT1SIRT3MKNK1 | |
| SCHEMBL5909485 | 0.78 | RAF1 (0.53) | RAF1MKNK1MKNK2HPGDSHPGD | |
| SCHEMBL9572445 | 0.78 | KMT2A (0.58) | SIRT2SIRT1SIRT3MKNK1MKNK2 | |
| SCHEMBL4267075 | 0.78 | MKNK1 (0.49) | RAF1SIRT2SIRT1SIRT3MKNK1 | |
| SCHEMBL29225084 | 0.77 | SIRT2 (0.43) | SIRT2SIRT1SIRT3MKNK1MKNK2 | |
| SCHEMBL28700532 | 0.77 | MEN1 (0.40) | SIRT2SIRT1SIRT3MKNK1MKNK2 | |
| SCHEMBL12923938 | 0.77 | MKNK1 (0.53) | RAF1SIRT2SIRT1SIRT3MKNK1 | |
| SCHEMBL6473892 | 0.76 | HPGD (0.54) | RAF1SIRT2SIRT1SIRT3MKNK1 | |
| SCHEMBL8262940 | 0.76 | SIRT2 (0.47) | RAF1SIRT2SIRT1SIRT3MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813293-A | Urea derivatives useful for the treatment of cancer | 蝎子疗法股份有限公司 | 2024-04-02 | — | — | CN | disclosed |