Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 2/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27947891 | 0.93 | MAPT (0.56) | MAPTLMNAGAAPOLBMAPK1 | |
| SCHEMBL2947690 | 0.86 | HDAC1 (0.43) | MAPTLMNAGAAPOLBMAPK1 | |
| SCHEMBL30136658 | 0.83 | GSK3A (0.41) | MAPTLMNAGAAPOLBGSK3A | |
| SCHEMBL20577141 | 0.82 | KCNH2 (0.40) | MAPTLMNAGAAPOLBMAPK1 | |
| SCHEMBL20577143 | 0.82 | KCNH2 (0.40) | MAPTLMNAGAAPOLBMAPK1 | |
| SCHEMBL20577148 | 0.82 | KCNH2 (0.40) | MAPTLMNAGAAPOLBMAPK1 | |
| SCHEMBL29225001 | 0.81 | ALDH1A1 (0.41) | MAPTLMNAGAAPOLBMAPK1 | |
| SCHEMBL25086292 | 0.80 | PRKCQ (0.50) | MAPTLMNAGAAPOLBGSK3A | |
| SCHEMBL12801758 | 0.78 | MAPT (0.36) | MAPTLMNAGAAPOLBMAPK1 | |
| SCHEMBL2793284 | 0.77 | GAA (0.58) | MAPTLMNAGAAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813293-A | Urea derivatives useful for the treatment of cancer | 蝎子疗法股份有限公司 | 2024-04-02 | — | — | CN | disclosed |