Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14863387 | 0.89 | ALK (0.42) | ALDH1A1CYP1A2NFKB1THPOPMP22 | |
| SCHEMBL26834042 | 0.85 | CYP19A1 (0.36) | CYP19A1MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL4771663 | 0.81 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1CYP3A4MAPT | |
| SCHEMBL29845809 | 0.81 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1CYP3A4MAPT | |
| SCHEMBL8973852 | 0.79 | CYP19A1 (0.56) | CYP19A1MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL29225986 | 0.79 | CYP19A1 (0.38) | CYP19A1MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL29226103 | 0.79 | CYP19A1 (0.38) | CYP19A1MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL24930071 | 0.79 | PDE4A (0.37) | HIF1APDE4ABACE1PDE4BCA1 | |
| SCHEMBL129694 | 0.79 | PDE4A (0.52) | POLBPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8973738 | 0.78 | CYP19A1 (0.57) | CYP19A1MEN1KMT2AALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240376046-A1 | PHENYL-SULFAMOYL-BENZOIC ACID DERIVATIVES AS ERAP1- MODULATORS | Grey Wolf Therapeutics Limited (GB) | 2024-11-14 | — | — | US | disclosed |
| CN-117881657-A | Phenyl-sulfamoyl-benzoic acid derivatives as ERAP1 modulators | 格雷沃尔夫治疗有限公司 | 2024-04-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240376046-A1 | PHENYL-SULFAMOYL-BENZOIC ACID DERIVATIVES AS ERAP1- MODULATORS | ERAP1, XPO1, RRP15 | CYP19A1 2081/4885MEN1 2922/4885KMT2A 1909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.