Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 15/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 12/20 | 0.46 |
| ▸ | KLK1 | P06870 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | F9 | P00740 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30995012 | 1.00 | F11 (0.46) | F11KLKB1KLK1KMT2AF9 | |
| SCHEMBL29022165 | 0.87 | F11 (0.49) | F11KLKB1KMT2A | |
| SCHEMBL30453237 | 0.87 | F11 (0.49) | F11KLKB1KMT2A | |
| SCHEMBL24633462 | 0.82 | F11 (0.46) | F11KLKB1 | |
| SCHEMBL16971478 | 0.79 | KMT2A (0.43) | F11KLKB1KLK1KMT2A | |
| SCHEMBL29227939 | 0.79 | F11 (0.45) | F11KLKB1KLK1KMT2AF9 | |
| SCHEMBL30995053 | 0.79 | F11 (0.45) | F11KLKB1KLK1KMT2AF9 | |
| SCHEMBL30995017 | 0.78 | F11 (0.48) | F11KLKB1 | |
| SCHEMBL30995015 | 0.78 | F11 (0.48) | F11KLKB1 | |
| SCHEMBL29227916 | 0.78 | F11 (0.48) | F11KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118126046-A | Substituted macrocyclic compound, and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2024-06-04 | — | — | CN | disclosed |