Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28529040 | 0.86 | SCN9A (0.53) | PPARASCN9APPARGKDM4EALDH1A1 | |
| SCHEMBL29229136 | 0.82 | MAOB (0.42) | MAOBCA1SLC1A1KMT2ATACR1 | |
| SCHEMBL29229134 | 0.82 | MAOB (0.42) | MAOBCA1SLC1A1KMT2ATACR1 | |
| SCHEMBL28976550 | 0.79 | POLB (0.32) | SCN9A | |
| SCHEMBL28533077 | 0.76 | PPARA (0.46) | PPARASCN9ACTSSPPARGCA1 | |
| SCHEMBL28763879 | 0.76 | PPARA (0.46) | PPARASCN9ACTSSPPARGCA1 | |
| SCHEMBL2897802 | 0.75 | PPARA (0.67) | PPARACTSSPPARGJAK3BTK | |
| SCHEMBL2897805 | 0.75 | PPARA (0.67) | PPARACTSSPPARGJAK3BTK | |
| SCHEMBL27580044 | 0.75 | PPARA (0.46) | PPARASCN9ACTSSPPARGCA1 | |
| SCHEMBL28506240 | 0.75 | POLB (0.33) | SCN9AJAK3BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117683051-A | Tetraheterocyclic compound, preparation method thereof, intermediate thereof and application thereof | 上海艾力斯医药科技股份有限公司 | 2024-03-12 | — | — | CN | disclosed |