Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28763879 | 0.88 | PPARA (0.46) | PPARACTSSSLC1A1PPARGCA1 | |
| SCHEMBL28533077 | 0.88 | PPARA (0.46) | PPARACTSSSLC1A1PPARGCA1 | |
| SCHEMBL27812309 | 0.84 | CTSK (0.48) | CTSSSCN9ANPC1MAPTRAB9A | |
| SCHEMBL27826715 | 0.79 | CTSS (0.50) | PPARACTSSPPARGGHSR | |
| SCHEMBL28240753 | 0.76 | CA1 (0.52) | PPARACTSSPPARGCA1SMN1; SMN2 | |
| SCHEMBL28921831 | 0.76 | CA1 (0.52) | PPARACTSSPPARGCA1SMN1; SMN2 | |
| SCHEMBL28995642 | 0.76 | SCN9A (0.41) | PPARACTSSPPARGSCN9AGHSR | |
| SCHEMBL29229250 | 0.75 | PPARA (0.42) | PPARACTSSSLC1A1PPARGCA1 | |
| SCHEMBL29060746 | 0.75 | CTSK (0.47) | CTSSSCN9ANPC1MAPTRAB9A | |
| SCHEMBL15311168 | 0.74 | CTSK (0.49) | CTSSCA1SCN9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1384835-A | Tricycle inhibitors of poly(ADP-ribose) polymerases | AGOURON PHARMA (US) | 2002-12-11 | — | — | CN | disclosed |