Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30842795 | 1.00 | TDP1 (0.42) | TDP1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL30842833 | 0.85 | MAPT (0.48) | TDP1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL29053285 | 0.85 | MAPT (0.48) | TDP1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13363917 | 0.80 | MAPT (0.61) | TDP1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL1120987 | 0.80 | CYP3A4 (0.58) | TDP1MEN1KMT2AKDM4EGAA | |
| SCHEMBL19674305 | 0.80 | MAPT (0.39) | TDP1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL31059891 | 0.78 | CYP3A4 (0.55) | TDP1KDM4EGAACYP3A4NPSR1 | |
| Bromide SCHEMBL8660152 | 0.78 | CYP3A4 (0.55) | TDP1KDM4EGAACYP3A4NPSR1 | |
| Water SCHEMBL1131752 | 0.78 | CYP3A4 (0.55) | TDP1KDM4EGAACYP3A4NPSR1 | |
| Water SCHEMBL1131329 | 0.78 | CYP3A4 (0.55) | TDP1KDM4EGAACYP3A4NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117700456-A | Arylamine photocatalyst and preparation method thereof, defluorinated mono-bridged ring propeller compound, preparation method and application thereof | 国科大杭州高等研究院 | 2024-03-15 | — | — | CN | claimed |
| CN-117700456-A | Arylamine photocatalyst and preparation method thereof, defluorinated mono-bridged ring propeller compound, preparation method and application thereof | 国科大杭州高等研究院 | 2024-03-15 | — | — | CN | disclosed |