Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 7/20 | 0.39 |
| ▸ | XIAP | P98170 | 4/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.35 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29230926 | 1.00 | CFD (0.39) | CFDXIAPDRD2S1PR4S1PR3 | |
| SCHEMBL29230936 | 1.00 | CFD (0.39) | CFDXIAPDRD2S1PR4S1PR3 | |
| SCHEMBL24665819 | 0.88 | HTRA1 (0.45) | CFDDRD2S1PR3 | |
| SCHEMBL29231182 | 0.88 | CFD (0.44) | CFDXIAPLMNA | |
| SCHEMBL29231188 | 0.88 | CFD (0.44) | CFDXIAPLMNA | |
| SCHEMBL29231187 | 0.88 | CFD (0.44) | CFDXIAPLMNA | |
| SCHEMBL24665612 | 0.87 | S1PR2 (0.34) | CFDXIAPDRD2S1PR4S1PR3 | |
| SCHEMBL24666031 | 0.87 | S1PR2 (0.34) | CFDXIAPDRD2S1PR4S1PR3 | |
| SCHEMBL24666492 | 0.87 | PSMB9 (0.42) | CFDPSMB9 | |
| SCHEMBL29230897 | 0.87 | S1PR2 (0.34) | CFDXIAPDRD2S1PR4S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117956985-A | Inhibitors of glycogen synthase 1 (GYS 1) and methods of use thereof | 梅兹治疗公司 | 2024-04-30 | — | — | CN | disclosed |