⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27899172 | 0.85 | ALDH1A1 (0.42) | — | |
| SCHEMBL27534 | 0.85 | — | — | |
| SCHEMBL28274756 | 0.82 | — | — | |
| SCHEMBL27909295 | 0.82 | — | — | |
| SCHEMBL28223603 | 0.82 | — | — | |
| SCHEMBL28109852 | 0.82 | — | — | |
| SCHEMBL28238490 | 0.82 | — | — | |
| SCHEMBL27569020 | 0.82 | — | — | |
| SCHEMBL645027 | 0.78 | — | — | |
| SCHEMBL28105671 | 0.74 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214342-A | 23-hydroxy betulinic acid 3-site modified derivative, preparation method and application | 中国药科大学 | 2021-08-06 | — | — | CN | claimed |
| CN-113214342-B | 23-hydroxy betulinic acid 3-site modified derivative, preparation method and application | 中国药科大学 | 2022-05-24 | — | — | CN | disclosed |
| CN-112824438-B | Synthetic method of polyimide | 湘潭大学 | 2022-05-17 | — | — | CN | disclosed |
| CN-110229333-B | Synthetic method of polyimide | 湘潭大学 | 2022-02-15 | — | — | CN | disclosed |
| CN-109076704-B | Flexible circuit board and manufacturing method thereof | 杜邦-东丽株式会社 | 2022-01-04 | — | — | CN | disclosed |
| CN-113214342-A | 23-hydroxy betulinic acid 3-site modified derivative, preparation method and application | 中国药科大学 | 2021-08-06 | — | — | CN | disclosed |
| CN-112824438-A | Novel synthesis method of polyimide | 湘潭大学 | 2021-05-21 | — | — | CN | disclosed |
| CN-112119077-A | Kinase inhibitors | 曼彻斯特大学 | 2020-12-22 | — | — | CN | disclosed |
| CN-108727259-A | Polysubstituted pyridine derivative and the preparation method and application thereof | 江苏师范大学 | 2018-11-02 | — | — | CN | disclosed |
| EP-2086538-B1 | COMBINATION THERAPIES FOR TREATING ALZHEIMER'S DISEASE USING DIMEBON AND DONEPEZIL | MEDIVATION NEUROLOGY INC (US) | 2012-03-14 | — | — | EP | disclosed |
| WO-2001096304-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |
| WO-2001096303-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |
| WO-2001096323-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |
| WO-2000076970-A2 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2000-12-21 | — | — | WO | disclosed |
| WO-2000076971-A2 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2000-12-21 | — | — | WO | disclosed |
| EP-1054887-A1 | BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | Amgen Inc. (US) | 2000-11-29 | — | — | EP | disclosed |
| US-6054472-A | IMMUNOSUPPRESSION, TREATING TRANSPLANT REJECTION WITH MERIMEPODIB | VERTEX PHARMACEUTICALS, INCORPORATED (US) | 2000-04-25 | — | — | US | disclosed |
| WO-1999040091-A1 | BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | AMGEN INC. (US) | 1999-08-12 | — | — | WO | disclosed |
| EP-0392059-A1 | Use of adamantane derivatives in the prevention and treatment of cerebral ischemia | Merz & Co. GmbH & Co. (DE) | 1990-10-17 | — | — | EP | disclosed |
| US-4043752-A | Phenylazoaminophenylpyrazole acid dye solutions containing two nonionic surfactants | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-08-23 | — | — | US | disclosed |