Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 20/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26816712 | 1.00 | CFD (0.42) | CFD | |
| SCHEMBL29231130 | 0.92 | CFD (0.41) | CFD | |
| SCHEMBL24666203 | 0.92 | CFD (0.41) | CFD | |
| SCHEMBL29820551 | 0.89 | CFD (0.39) | CFD | |
| SCHEMBL26816629 | 0.89 | CFD (0.39) | CFD | |
| SCHEMBL30341372 | 0.89 | CFD (0.39) | CFD | |
| SCHEMBL29230861 | 0.89 | CFD (0.39) | CFD | |
| SCHEMBL26816112 | 0.89 | CFD (0.39) | CFD | |
| SCHEMBL29230978 | 0.89 | CFD (0.39) | CFD | |
| SCHEMBL29230748 | 0.89 | CFD (0.41) | CFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117956985-A | Inhibitors of glycogen synthase 1 (GYS 1) and methods of use thereof | 梅兹治疗公司 | 2024-04-30 | — | — | CN | disclosed |
| EP-4308095-A1 | INHIBITORS OF GLYCOGEN SYNTHASE 1 (GYS1) AND METHODS OF USE THEREOF | Maze Therapeutics, Inc. (US) | 2024-01-24 | — | — | EP | disclosed |
| WO-2022198196-A1 | INHIBITORS OF GLYCOGEN SYNTHASE 1 (GYS1) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2022-09-22 | — | — | WO | disclosed |