Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 15/20 | 0.38 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24666276 | 1.00 | CFD (0.38) | CFDPSMB9XIAPMEN1ALDH1A1 | |
| SCHEMBL24666217 | 1.00 | CFD (0.38) | CFDPSMB9XIAPMEN1ALDH1A1 | |
| SCHEMBL24665428 | 1.00 | CFD (0.38) | CFDPSMB9XIAPMEN1ALDH1A1 | |
| SCHEMBL29230659 | 0.92 | CFD (0.35) | CFDPSMB9XIAP | |
| SCHEMBL29230559 | 0.92 | CFD (0.35) | CFDPSMB9XIAP | |
| SCHEMBL24665821 | 0.92 | CFD (0.35) | CFDPSMB9XIAP | |
| SCHEMBL30341516 | 0.91 | CFD (0.38) | CFD | |
| SCHEMBL29231193 | 0.91 | CFD (0.38) | CFD | |
| SCHEMBL29820287 | 0.91 | CFD (0.38) | CFD | |
| SCHEMBL30341362 | 0.91 | CFD (0.38) | CFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117956985-A | Inhibitors of glycogen synthase 1 (GYS 1) and methods of use thereof | 梅兹治疗公司 | 2024-04-30 | — | — | CN | disclosed |