SCHEMBL29232003

SCHEMBL29232003

O=C(O)C(O)C(O)C(=O)OC(=O)[C@H](O)[C@@H](O)C(=O)OC(=O)C(O)C(O)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.62
TP53 P04637 1/20 0.35
HTT P42858 1/20 0.35
CYP2C9 P11712 1/20 0.35
PDE4A P27815 1/20 0.35
PGD P52209 1/20 0.34
NFKB1 P19838 1/20 0.33
CYP2C19 P33261 1/20 0.33
OR51E2 Q9H255 1/20 0.30
LMNA P02545 1/20 0.30
ALDH1A1 P00352 1/20 0.30
THRB P10828 1/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9862728 1.00 TSHR (0.62) TSHRTP53HTTCYP2C9PDE4A
SCHEMBL1397720 1.00 TSHR (0.62) TSHRTP53HTTCYP2C9PDE4A
SCHEMBL14742965 0.97 TSHR (0.59) TSHRTP53HTTCYP2C9PDE4A
SCHEMBL9439905 0.94 TSHR (0.56) TSHRTP53HTTCYP2C9PDE4A
SCHEMBL7992773 0.94 TSHR (0.56) TSHRTP53HTTCYP2C9PDE4A
SCHEMBL1580351 0.94 TSHR (0.56) TSHRTP53HTTCYP2C9PDE4A
Water SCHEMBL28238706 0.92 TSHR (0.53) TSHRTP53HTTCYP2C9PDE4A
SCHEMBL10629208 0.92 TSHR (0.53) TSHRTP53HTTCYP2C9PDE4A
Cadaverine Tartrate SCHEMBL8046839 0.89 TSHR (0.50) TSHRTP53HTTCYP2C9PDE4A
Butanedione SCHEMBL52101 0.89 TSHR (0.50) TSHRTP53HTTCYP2C9PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115190815-B Arylcyclohexylamine derivatives and their use in the treatment of psychotic disorders 吉尔伽美什制药公司 2024-06-18 CN disclosed