Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HBB | P68871 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29232887 | 0.96 | KDM4E (0.40) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL29232897 | 0.91 | KDM4E (0.46) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL29232911 | 0.85 | TP53 (0.39) | KDM4EALDH1A1HSD17B10HPGDTDP1 | |
| SCHEMBL29232905 | 0.84 | ELANE (0.49) | ALDH1A1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL29232915 | 0.81 | TP53 (0.39) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL29232906 | 0.80 | ELANE (0.49) | ALDH1A1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL29232900 | 0.77 | KDM4E (0.47) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL29232881 | 0.75 | MAPT (0.52) | MAPTMEN1KMT2AMAPK1HTT | |
| SCHEMBL29232882 | 0.74 | KDM4E (0.35) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL29232908 | 0.70 | MAPT (0.49) | KDM4EALDH1A1MAPTHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118206560-A | Lipoic acid derivative containing pyridazino indole structure, and preparation method and application thereof | 浙江中医药大学 | 2024-06-18 | — | — | CN | disclosed |