Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 9/20 | 0.49 |
| ▸ | F2 | P00734 | 6/20 | 0.49 |
| ▸ | PLAU | P00749 | 6/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 6/20 | 0.49 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29232906 | 0.96 | ELANE (0.49) | ELANEF2PLAUCTRB1KLKB1 | |
| SCHEMBL29232881 | 0.92 | MAPT (0.52) | ELANEF2PLAUCTRB1KLKB1 | |
| SCHEMBL29232890 | 0.86 | ELANE (0.52) | ELANEF2PLAUCTRB1KLKB1 | |
| SCHEMBL29232886 | 0.84 | KDM4E (0.40) | ELANEMAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL29232892 | 0.82 | ELANE (0.52) | ELANEF2PLAUCTRB1KLKB1 | |
| SCHEMBL29232887 | 0.80 | KDM4E (0.40) | ELANEMAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL29233023 | 0.80 | MAPT (0.53) | ELANEF2PLAUCTRB1KLKB1 | |
| SCHEMBL29233021 | 0.78 | MAPT (0.49) | ELANEF2PLAUCTRB1KLKB1 | |
| SCHEMBL29232897 | 0.74 | KDM4E (0.46) | ELANEMAPTMEN1KMT2ALMNA | |
| SCHEMBL148001 | 0.71 | MAPT (0.85) | MAPTMEN1KMT2ALMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118206560-A | Lipoic acid derivative containing pyridazino indole structure, and preparation method and application thereof | 浙江中医药大学 | 2024-06-18 | — | — | CN | disclosed |