Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NGFR | P08138 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29232908 | 0.95 | MAPT (0.49) | MAPTALDH1A1NGFRDYRK1AGABRA1 | |
| SCHEMBL29232883 | 0.88 | NGFR (0.49) | MAPTALDH1A1NGFRDYRK1AEGFR | |
| SCHEMBL29232880 | 0.82 | MAPT (0.51) | MAPTALDH1A1GABRA1GABRA5GABRA3 | |
| SCHEMBL29232879 | 0.78 | MAPT (0.51) | MAPTALDH1A1GABRA1GABRA5GABRA3 | |
| SCHEMBL29232915 | 0.72 | TP53 (0.39) | MAPTALDH1A1GABRA1GABRA5GABRA3 | |
| SCHEMBL173308 | 0.72 | KDM4E (0.65) | ALDH1A1DYRK1AKDM4EGAAPRKAG1 | |
| SCHEMBL29232889 | 0.71 | MAPT (0.54) | MAPTALDH1A1GABRA1GABRA5GABRA3 | |
| SCHEMBL13684477 | 0.71 | ALDH1A1 (0.57) | MAPTALDH1A1NGFRKDM4ELMNA | |
| SCHEMBL29232885 | 0.70 | NGFR (0.47) | NGFRDYRK1AGABRA1GABRA5GABRA3 | |
| SCHEMBL29232911 | 0.70 | TP53 (0.39) | ALDH1A1GABRA1GABRA5GABRA3GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118206560-A | Lipoic acid derivative containing pyridazino indole structure, and preparation method and application thereof | 浙江中医药大学 | 2024-06-18 | — | — | CN | disclosed |