SCHEMBL29233169

SCHEMBL29233169

C=CC(=O)OCCCCC(C)N=C=O

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.53
ALDH1A1 P00352 4/20 0.53
CYP3A4 P08684 2/20 0.53
HPGD P15428 1/20 0.49
TP53 P04637 3/20 0.41
HIF1A Q16665 3/20 0.41
HSD17B10 Q99714 1/20 0.41
THRB P10828 2/20 0.36
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
ATM Q13315 1/20 0.33
HCAR2 Q8TDS4 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29062277 0.89 TSHR (0.46) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL648008 0.79 TSHR (0.58) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL1259928 0.79 TSHR (0.67) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL6864736 0.78 TSHR (0.51) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL25281286 0.77 TSHR (0.70) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL25228041 0.77 TSHR (0.70) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL35574 0.77 TSHR (0.70) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL25275202 0.77 TSHR (0.70) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL20503422 0.77 TSHR (0.70) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL1260225 0.77 TSHR (0.70) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118215651-A Method for producing isocyanate compound, method for producing urethane compound, method for recovering amine compound, and isocyanate composition 旭化成株式会社 2024-06-18 CN disclosed