Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1906864 | 0.87 | TSHR (0.49) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL29233078 | 0.86 | TSHR (0.48) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL29233099 | 0.82 | TSHR (0.45) | TSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL20719906 | 0.81 | TSHR (0.50) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL11215129 | 0.81 | TSHR (0.49) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL20719910 | 0.79 | TSHR (0.57) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL20719909 | 0.78 | TSHR (0.52) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL29233169 | 0.78 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL20719916 | 0.77 | TSHR (0.51) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL20719905 | 0.77 | TSHR (0.51) | TSHRHPGDALDH1A1CYP3A4THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6803168-B1 | ACRYLIC OR METHACRYLIC POLYMER WITH AN ISOCYANATE GROUP BONDED THROUGH AN ALKYLENE GROUP TO A SIDE CHAIN THEREOF OR WITH AN AMINO OR HYDROXYL GROUP-CONTAINING ORGANIC CHROMOPHORE WHICH ABSORBS RADIATION IN THE RANGE OF 100 TO 450 NM WAVELENGTH | CLARIANT FINANCE (BVI) LIMITED (VG) | 2004-10-12 | — | — | US | disclosed |
| EP-0917002-B1 | COMPOSITION FOR ANTIREFLECTION OR LIGHT ABSORPTION FILM AND COMPOUNDS FOR USE IN THE SAME | CLARIANT FINANCE BVI LTD (VG) | 2004-03-17 | — | — | EP | disclosed |
| EP-0917002-A1 | COMPOSITION FOR ANTIREFLECTION OR LIGHT ABSORPTION FILM AND COMPOUNDS FOR USE IN THE SAME | CLARIANT INTERNATIONAL LTD. (CH) | 1999-05-19 | — | — | EP | disclosed |