SCHEMBL29233356

SCHEMBL29233356

Cn1cc(C(F)(F)F)nc1-c1ccc(Cc2ncc[n+](N)c2N)cc1

nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ USP1 O94782 20/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30485247 1.00 USP1 (0.41) USP1
SCHEMBL30939412 0.87 USP1 (0.38) USP1
SCHEMBL29233355 0.87 USP1 (0.38) USP1
SCHEMBL26442519 0.83 USP1 (0.44) USP1
SCHEMBL30816562 0.81 USP1 (0.44) USP1
SCHEMBL30966307 0.80 USP1 (0.43) USP1
SCHEMBL30966290 0.78 USP1 (0.48) USP1
SCHEMBL22122099 0.75 USP1 (0.46) USP1
SCHEMBL18865620 0.74 USP1 (0.48) USP1
SCHEMBL21821550 0.73 USP1 (0.42) USP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118215664-A Substituted triazoloheteroaryl compounds as USP1 inhibitors and uses thereof 上海瑛派药业有限公司 2024-06-18 — — CN disclosed
Send feedback