Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT8 | Q16880 | 7/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.38 |
| ▸ | CDK2 | P24941 | 5/20 | 0.38 |
| ▸ | APOL1 | O14791 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | LIPC | P11150 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21813599 | 0.73 | UGT8 (0.54) | UGT8CCNE1CDK2LIPCLIPG | |
| SCHEMBL21813597 | 0.73 | UGT8 (0.54) | UGT8CCNE1CDK2LIPCLIPG | |
| SCHEMBL21862454 | 0.72 | UGT8 (0.65) | UGT8 | |
| SCHEMBL21862452 | 0.66 | UGT8 (1.00) | UGT8 | |
| SCHEMBL30686905 | 0.66 | UGT8 (1.00) | UGT8 | |
| SCHEMBL21813775 | 0.65 | UGT8 (0.63) | UGT8HRH3ACACB | |
| SCHEMBL21813779 | 0.65 | UGT8 (0.63) | UGT8HRH3ACACB | |
| SCHEMBL13753672 | 0.61 | HPGD (0.65) | SMN1; SMN2 | |
| SCHEMBL30519107 | 0.59 | EPHX1 (0.46) | CCNE1CDK2CYP2C19 | |
| SCHEMBL27311169 | 0.59 | EPHX1 (0.46) | CCNE1CDK2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423711-B | Thieno [3,2-B ] pyridine derivatives as UDP glycosyltransferase inhibitors and methods of use thereof | 建新公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-113423711-A | Thieno [3,2-B ] pyridine derivatives as UDP glycosyltransferase inhibitors and methods of use thereof | 建新公司 | 2021-09-21 | — | — | CN | disclosed |