SCHEMBL2923385

SCHEMBL2923385

NN1C(=O)OCC1c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 10/20 0.42
ALDH1A1 P00352 1/20 0.39
GAA P10253 1/20 0.39
HTT P42858 1/20 0.39
NPC1 O15118 1/20 0.39
LMNA P02545 1/20 0.39
TP53 P04637 1/20 0.39
HPGD P15428 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
MEN1 O00255 1/20 0.39
POLB P06746 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20408769 0.82 CYP19A1 (0.39) ALDH1A1HTTLMNATP53MEN1
SCHEMBL18264226 0.78 CYP19A1 (0.43) ALDH1A1GAANPC1LMNATP53
SCHEMBL5281441 0.78 IDH1 (0.42) IDH1ALDH1A1GAAHTTNPC1
SCHEMBL5286742 0.78 IDH1 (0.43) IDH1ALDH1A1
SCHEMBL5286737 0.78 IDH1 (0.42) IDH1ALDH1A1GAAHTTNPC1
SCHEMBL5281444 0.78 IDH1 (0.43) IDH1ALDH1A1
SCHEMBL2615701 0.78 IDH1 (0.43) IDH1ALDH1A1
SCHEMBL8138150 0.77 HDAC1 (0.44) IDH1ALDH1A1GAAHTTNPC1
SCHEMBL5431723 0.76 QPCT (0.51) IDH1
SCHEMBL5430336 0.76 QPCT (0.51) IDH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0848053-B1 Mixtures of esterified carboxy-containing interpolymers and lubricants containing them LUBRIZOL CORP (US) 2010-09-29 EP disclosed
EP-0853115-B1 Additive concentrates containing mixtures of organic diluents and esterified carboxy-containing interpolymers and lubricants containing them LUBRIZOL CORP (US) 2004-11-17 EP disclosed
US-5880074-A ADDITIVE CONCENTRATE COMPRISING DILUENT SELECTED FROM SYNTHETIC OIL OR NAPHTHENIC OILS, AN ESTER DERIVED FROM A CARBOXY-CONTAINING INTERPOLYMER HAVING REDUCED SPECIFIC VISCOSITY; GOOD LOW TEMPERATURE CHARACTERISTICS LUBRIZOL CORPORATION THE 1999-03-09 US disclosed
EP-0853115-A1 Additive concentrates containing mixtures of organic diluents and esterified carboxy-containing interpolymers and lubricants containing them The Lubrizol Corporation (US) 1998-07-15 EP disclosed
EP-0848053-A1 Mixtures of esterified carboxy-containing interpolymers and lubricants containing them The Lubrizol Corporation (US) 1998-06-17 EP disclosed
US-5707943-A EXTREME TEMPERATURE ADDITIVES, POUR POINT DEPRESSANTS, AMIDATION, ESTERIFICATION, TRANSESTERIFICATION, TRANSAMIDATION OF ACRYLIC ACID OR ANHYDRIDE COPOLYMERS THE LUBRIZOL CORPORATION (US) 1998-01-13 US disclosed
EP-0203991-B1 POLYMERIC COMPOSITIONS, OIL COMPOSITIONS CONTAINING SAID POLYMERIC COMPOSITIONS, TRANSMISSION FLUIDS AND HYDRAULIC FLUIDS The Lubrizol Corporation (US) 1992-05-27 EP disclosed
EP-0265520-A1 MODIFIED ASPHALT COMPOSITIONS The Lubrizol Corporation (US) 1988-05-04 EP disclosed
US-4734446-A TRANSMISSION FLUIDS, HYDRAULIC FLUIDS THE LUBRIZOL CORPORATION (US) 1988-03-29 US disclosed
WO-1987006947-A1 MODIFIED ASPHALT COMPOSITIONS THE LUBRIZOL CORPORATION (US) 1987-11-19 WO disclosed
US-4677146-A Modified asphalt compositions comprising a nitrogen derivative of an esterified copolymer THE LUBRIZOL CORPORATION (US) 1987-06-30 US disclosed
US-4654403-A ADDITIVES IN TRANSMISSION AND HYDRAULIC FLUIDS THE LUBRIZOL CORPORATION (US) 1987-03-31 US disclosed
EP-0203991-A1 POLYMERIC COMPOSITIONS, OIL COMPOSITIONS CONTAINING SAID POLYMERIC COMPOSITIONS, TRANSMISSION FLUIDS AND HYDRAULIC FLUIDS. LUBRIZOL CORP (US) 1986-12-10 EP disclosed
US-4594378-A Blend of oil soluble homopolymer of non-aromatic mono-olefin and nitrogen-containing ester of a carboxy containing interpolymer THE LUBRIZOL CORPORATION (US) 1986-06-10 US disclosed
WO-1986003221-A1 POLYMERIC COMPOSITIONS, OIL COMPOSITIONS CONTAINING SAID POLYMERIC COMPOSITIONS, TRANSMISSION FLUIDS AND HYDRAULIC FLUIDS THE LUBRIZOL CORPORATION (US) 1986-06-05 WO disclosed
US-3933761-A INTERPOLYMERS THE LUBRIZOL CORPORATION (US) 1976-01-20 US disclosed