Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 9/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5281444 | 1.00 | IDH1 (0.43) | IDH1ALDH1A1ATMCHRNB2CHRNB4 | |
| SCHEMBL2615701 | 1.00 | IDH1 (0.43) | IDH1ALDH1A1ATMCHRNB2CHRNB4 | |
| SCHEMBL3652984 | 0.82 | CHRNA7 (0.43) | ALDH1A1CHRNA7 | |
| SCHEMBL6903965 | 0.82 | CYP19A1 (0.39) | — | |
| SCHEMBL3652982 | 0.82 | CHRNA7 (0.43) | ALDH1A1CHRNA7 | |
| SCHEMBL3654550 | 0.82 | CHRNA7 (0.43) | ALDH1A1CHRNA7 | |
| SCHEMBL16181385 | 0.80 | CYP19A1 (0.45) | ALDH1A1 | |
| SCHEMBL2235912 | 0.80 | DDB1 (0.38) | — | |
| SCHEMBL2235902 | 0.80 | DDB1 (0.38) | — | |
| SCHEMBL6904113 | 0.80 | KDM4E (0.58) | IDH1ALDH1A1CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | claimed |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. (US) | 2006-09-21 | — | — | US | claimed |
| EP-3464297-B1 | PROCESS FOR PREPARATION OF ERIBULIN AND INTERMEDIATES THEREOF | Dr Reddys Laboratories Ltd (IN) | 2023-10-25 | — | — | EP | disclosed |
| US-11059799-B2 | Process for preparation of eribulin and intermediates thereof | DR. REDDY'S LABORATORIES LIMITED. (IN) | 2021-07-13 | — | — | US | disclosed |
| US-20210163509-A1 | Intermediates useful in the preparation of halichondrin compounds and methods for preparing the same | BEIJING TIENYI LUFU PHARMATECH CO. LTD. (CN) | 2021-06-03 | — | — | US | disclosed |
| US-10836776-B2 | Process for preparation of eribulin and intermediates thereof | DR. REDDY'S LABORATORIES LIMITED (IN) | 2020-11-17 | — | — | US | disclosed |
| US-20190276470-A1 | PROCESS FOR PREPARATION OF ERIBULIN AND INTERMEDIATES THEREOF | DR. REDDY'S LABORATORIES LIMITED (IN) | 2019-09-12 | — | — | US | disclosed |
| US-20190177291-A1 | PROCESS FOR PREPARATION OF ERIBULIN AND INTERMEDIATES THEREOF | DR. REDDY'S LABORATORIES LIMITED (IN) | 2019-06-13 | — | — | US | disclosed |
| WO-2019055913-A1 | COMPOSITIONS AND METHODS FOR TREATING BRAIN INJURY | AZEVAN PHARMACEUTICALS, INC. (US) | 2019-03-21 | — | — | WO | disclosed |
| WO-2017203459-A1 | PROCESS FOR PREPARATION OF ERIBULIN AND INTERMEDIATES THEREOF | DR. REDDY'S LABORATORIES LIMITED (IN) | 2017-11-30 | — | — | WO | disclosed |
| US-20170204065-A1 | PROCESS FOR THE PREPARATION OF KINASE INHIBITORS AND INTERMEDIATES THEREOF | ALCON INC. (CH) | 2017-07-20 | — | — | US | disclosed |
| US-20170137384-A1 | PROCESS FOR THE PREPARATION OF KINASE INHIBITORS AND INTERMEDIATES THEREOF | ALCON INC. (CH) | 2017-05-18 | — | — | US | disclosed |
| US-9643927-B1 | Process for the preparation of kinase inhibitors and intermediates thereof | AERIE PHARMACEUTICALS, INC. (US) | 2017-05-09 | — | — | US | disclosed |
| WO-2013151161-A1 | NOVEL COMPOUND, METHOD FOR PRODUCING SAME AND ANTITUMOR AGENT | 学校法人東京理科大学 (JP) | 2013-10-10 | — | — | WO | disclosed |
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. (US) | 2006-09-21 | — | — | US | disclosed |
| US-5391819-A | Process of making chiral 2-aryl-1,4-butanediamine derivatives as useful neurokinin-A antagonists | MERCK & CO., INC. (US) | 1995-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11059799-B2 | Process for preparation of eribulin and intermediates thereof | ERLIN1, ERLIN2, MAN1B1 | IDH1 1148/4885ALDH1A1 1325/4885ATM 3916/4885 |
| US-10836776-B2 | Process for preparation of eribulin and intermediates thereof | ERLIN1, ERLIN2, DHPS | IDH1 802/4885ALDH1A1 1861/4885ATM 3999/4885 |
| US-20170137384-A1 | PROCESS FOR THE PREPARATION OF KINASE INHIBITORS AND INTERMEDIATES THEREOF | MAP3K1, MAP3K6, MAP3K7 | IDH1 440/4885ALDH1A1 2948/4885ATM 375/4885 |
| US-20170204065-A1 | PROCESS FOR THE PREPARATION OF KINASE INHIBITORS AND INTERMEDIATES THEREOF | MAP3K1, MAP3K6, MAP3K7 | IDH1 440/4885ALDH1A1 2948/4885ATM 375/4885 |
| US-20190177291-A1 | PROCESS FOR PREPARATION OF ERIBULIN AND INTERMEDIATES THEREOF | ERLIN1, ERLIN2, MAN1B1 | IDH1 1148/4885ALDH1A1 1325/4885ATM 3916/4885 |
| US-20210163509-A1 | Intermediates useful in the preparation of halichondrin compounds and methods for preparing the same | ERLIN1, ERLIN2, MAN1B1 | IDH1 691/4885ALDH1A1 1342/4885ATM 4281/4885 |
| US-20190276470-A1 | PROCESS FOR PREPARATION OF ERIBULIN AND INTERMEDIATES THEREOF | ERLIN1, ERLIN2, DHPS | IDH1 802/4885ALDH1A1 1861/4885ATM 3999/4885 |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | CLSPN, LMAN2, RPN2 | IDH1 4439/4885ALDH1A1 2972/4885ATM 4711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.