Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 1/20 | 0.69 |
| ▸ | P2RY4 | P51582 | 7/20 | 0.63 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.56 |
| ▸ | GNG2 | P59768 | 4/20 | 0.52 |
| ▸ | GNB1 | P62873 | 4/20 | 0.52 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ENTPD1 | P49961 | 1/20 | 0.49 |
| ▸ | ENTPD2 | Q9Y5L3 | 1/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29234761 | 0.92 | P2RY2 (0.68) | P2RY2P2RY4P2RY12ENTPD1ENTPD2 | |
| SCHEMBL19948045 | 0.92 | P2RY2 (0.81) | P2RY2P2RY4P2RY12GNG2GNB1 | |
| SCHEMBL29355096 | 0.92 | P2RY2 (0.81) | P2RY2P2RY4P2RY12GNG2GNB1 | |
| SCHEMBL29354313 | 0.87 | GNG2 (0.66) | P2RY2P2RY4P2RY12GNG2GNB1 | |
| SCHEMBL13214120 | 0.87 | GNG2 (0.66) | P2RY2P2RY4P2RY12GNG2GNB1 | |
| SCHEMBL792523 | 0.86 | GNG2 (0.65) | P2RY2P2RY4P2RY12GNG2GNB1 | |
| SCHEMBL13214031 | 0.82 | P2RY4 (0.79) | P2RY2P2RY4P2RY12GNG2GNB1 | |
| SCHEMBL11425002 | 0.82 | GNG2 (0.68) | P2RY2P2RY4P2RY12GNG2GNB1 | |
| SCHEMBL3028638 | 0.81 | P2RY4 (0.78) | P2RY2P2RY4P2RY12GNG2GNB1 | |
| SCHEMBL13214024 | 0.81 | P2RY4 (0.70) | P2RY2P2RY4P2RY12GNG2GNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112888696-B | Exonuclease inhibitors and methods of use thereof | 德琪医疗有限公司 | 2024-04-16 | — | — | CN | disclosed |