Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 6/20 | 0.80 |
| ▸ | HTR3E | A5X5Y0 | 4/20 | 0.80 |
| ▸ | HTR3B | O95264 | 4/20 | 0.80 |
| ▸ | HTR3A | P46098 | 4/20 | 0.80 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 0.80 |
| ▸ | HTR3C | Q8WXA8 | 4/20 | 0.80 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.80 |
| ▸ | HTR1A | P08908 | 2/20 | 0.62 |
| ▸ | HTR7 | P34969 | 2/20 | 0.62 |
| ▸ | LTA4H | P09960 | 1/20 | 0.58 |
| ▸ | HTR2C | P28335 | 2/20 | 0.57 |
| ▸ | HTR6 | P50406 | 5/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylpiperazine SCHEMBL27606301 | 0.90 | ADRB1 (0.91) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| Phenylpiperazine SCHEMBL24889 | 0.89 | ADRB1 (1.00) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| Phenylpiperazine SCHEMBL27858598 | 0.89 | ADRB1 (1.00) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| Phenylpiperazine SCHEMBL55125 | 0.89 | ADRB1 (1.00) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| Phenylpiperazine SCHEMBL29135595 | 0.89 | ADRB1 (1.00) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| Phenylpiperazine SCHEMBL11430796 | 0.87 | ADRB1 (0.95) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| Phenylpiperazine SCHEMBL15327472 | 0.87 | ADRB1 (0.95) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| Phenylpiperazine SCHEMBL10675573 | 0.87 | ADRB1 (0.95) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| Phenylpiperazine SCHEMBL11728031 | 0.87 | ADRB1 (0.95) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL17431870 | 0.87 | ADRB1 (0.95) | ADRB1HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118221620-A | Benzamide phenylpiperazine radioactive compound and preparation method and application thereof | 中国科学院高能物理研究所 | 2024-06-21 | — | — | CN | claimed |
| CN-118221620-A | Benzamide phenylpiperazine radioactive compound and preparation method and application thereof | 中国科学院高能物理研究所 | 2024-06-21 | — | — | CN | disclosed |
| CN-118221620-A | Benzamide phenylpiperazine radioactive compound and preparation method and application thereof | 中国科学院高能物理研究所 | 2024-06-21 | — | — | CN | disclosed |