SCHEMBL29236239

SCHEMBL29236239

COC(=O)c1ccccc1-c1ccc2c(Cl)cccc2c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 4/20 0.68
SLC6A4 P31645 3/20 0.68
SLC6A2 P23975 1/20 0.68
ROCK2 O75116 1/20 0.48
CSF1R P07333 1/20 0.48
KDR P35968 1/20 0.48
FLT3 P36888 1/20 0.48
GSK3A P49840 1/20 0.48
GSK3B P49841 1/20 0.48
CDK5 Q00535 1/20 0.48
ROCK1 Q13464 1/20 0.48
SLK Q9H2G2 1/20 0.48
IRAK4 Q9NWZ3 1/20 0.48
HSD17B3 P37058 1/20 0.44
PDK2 Q15119 1/20 0.44
ALDH1A1 P00352 4/20 0.44
KDM4E B2RXH2 2/20 0.44
HPGD P15428 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
NR4A2 P43354 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29236145 0.83 MCL1 (0.50) SLC6A3SLC6A4SLC6A2ALDH1A1NR4A2
SCHEMBL16683936 0.82 SLC6A3 (1.00) SLC6A3SLC6A4SLC6A2ROCK2CSF1R
SCHEMBL28893993 0.81 SLC6A3 (0.64) SLC6A3SLC6A4SLC6A2ROCK2CSF1R
SCHEMBL13153612 0.79 SLC6A3 (0.88) SLC6A3SLC6A4SLC6A2ROCK2CSF1R
SCHEMBL13152936 0.79 SLC6A3 (0.88) SLC6A3SLC6A4SLC6A2ROCK2CSF1R
SCHEMBL2114712 0.79 ESR1 (0.52) SLC6A3SLC6A4SLC6A2ROCK2CSF1R
SCHEMBL30285287 0.78 SLC6A3 (0.71) SLC6A3SLC6A4SLC6A2ROCK2CSF1R
SCHEMBL30285060 0.77 SLC6A3 (0.69) SLC6A3SLC6A4SLC6A2ROCK2CSF1R
SCHEMBL22920852 0.76 SLC6A3 (0.56) SLC6A3SLC6A4SLC6A2ROCK2CSF1R
SCHEMBL10392253 0.76 LCK (0.56) ALDH1A1HPGDMAPTKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117730639-A Organic electronic device comprising a compound of formula (I), display device comprising said organic electronic device, and compound of formula (I) 诺瓦尔德股份有限公司 2024-03-19 CN disclosed