SCHEMBL292363

SCHEMBL292363

COC(=O)/C=C/c1ccc(Nc2ccccc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.62
CA1 P00915 1/20 0.62
CA2 P00918 1/20 0.62
TYR P14679 1/20 0.62
CA7 P43166 1/20 0.62
CA9 Q16790 1/20 0.62
CA14 Q9ULX7 1/20 0.62
PTPN1 P18031 1/20 0.54
TTR P02766 1/20 0.53
APP P05067 1/20 0.53
SIRT2 Q8IXJ6 1/20 0.51
SIRT1 Q96EB6 1/20 0.51
MMP1 P03956 3/20 0.50
MMP2 P08253 3/20 0.50
MMP9 P14780 3/20 0.50
EGFR P00533 2/20 0.50
EPHX2 P34913 1/20 0.49
MAOA P21397 1/20 0.49
MAOB P27338 1/20 0.49
KMT2A Q03164 5/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL292364 1.00 CA12 (0.62) CA12CA1CA2TYRCA7
SCHEMBL5050282 0.87 CA12 (0.58) CA12CA1CA2TYRCA7
SCHEMBL13899903 0.86 CA12 (0.70) CA12CA1CA2TYRCA7
E-Methyl Cinnamate SCHEMBL112062 0.86 CA12 (0.69) CA12CA1CA2TYRCA7
E-Methyl Cinnamate SCHEMBL101530 0.86 CA12 (0.69) CA12CA1CA2TYRCA7
E-Methyl Cinnamate SCHEMBL27554805 0.86 CA12 (0.69) CA12CA1CA2TYRCA7
E-Methyl Cinnamate SCHEMBL1862419 0.86 CA12 (0.69) CA12CA1CA2TYRCA7
E-Methyl Cinnamate SCHEMBL901224 0.86 CA12 (0.69) CA12CA1CA2TYRCA7
E-Methyl Cinnamate SCHEMBL2425288 0.86 CA12 (0.69) CA12CA1CA2TYRCA7
E-Methyl Cinnamate SCHEMBL27554806 0.86 CA12 (0.69) CA12CA1CA2TYRCA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3851489-A1 MODIFIED MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, RESIN COMPOSITION, TIRE AND RESIN PRODUCT BRIDGESTONE CORPORATION (JP) 2021-07-21 EP disclosed
WO-2020054484-A1 MODIFIED MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, RESIN COMPOSITION, TIRE AND RESIN PRODUCT 株式会社ブリヂストン 2020-03-19 WO disclosed
US-20180244808-A1 METHOD FOR PRODUCING MODIFIED DIENE-BASED RUBBER, RUBBER COMPOSITION AND TIRE BRIDGESTONE CORPORATION (JP) 2018-08-30 US disclosed
EP-3345933-A1 METHOD FOR PRODUCING MODIFIED DIENE RUBBER, RUBBER COMPOSITION, AND TIRE Bridgestone Corporation (JP) 2018-07-11 EP disclosed
EP-2845869-B1 MODIFIED NATURAL RUBBER, METHOD FOR PRODUCING SAME, RUBBER COMPOSITION, AND TIRE BRIDGESTONE CORP (JP) 2018-01-17 EP disclosed
US-9428619-B2 Interpolymers containing isobutylene and diene mer units BRIDGESTONE CORPORATION (JP) 2016-08-30 US disclosed
US-9181378-B2 Modified natural rubber and method of manufacturing the same, rubber composition and tire BRIDGESTONE CORPORATION (JP) 2015-11-10 US disclosed
US-9132697-B2 Modified natural rubber or modified natural rubber latex, and rubber composition and pneumatic tire BRIDGESTONE CORPORATION (JP) 2015-09-15 US disclosed
EP-2845869-A1 MODIFIED NATURAL RUBBER, METHOD FOR PRODUCING SAME, RUBBER COMPOSITION, AND TIRE Bridgestone Corporation (JP) 2015-03-11 EP disclosed
US-8960247-B2 Pneumatic tire BRIDGESTONE CORPORATION (JP) 2015-02-24 US disclosed
EP-1215226-B1 Diene-based rubber/inorganic compound complexes, methods for producing the same and rubber compositions containing the same JSR CORP (JP) 2006-06-07 EP disclosed
EP-1629021-A1 MODIFIED NATURAL RUBBER OR MODIFIED NATURAL RUBBER LATEX, AND RUBBER COMPOSITION AND PNEUMATIC TIRE Bridgestone Corporation (JP) 2006-03-01 EP disclosed
US-20050182159-A1 Diene rubber-inorganic compound composite and process for producing the same JRS CORPORATION (JP) 2005-08-18 US disclosed
EP-1500679-A1 DIENE RUBBER/INORGANIC COMPOUND COMPOSITE AND PROCESS FOR PRODUCING THE SAME JSR Corporation (JP) 2005-01-26 EP disclosed
WO-2004106397-A1 MODIFIED NATURAL RUBBER OR MODIFIED NATURAL RUBBER LATEX, AND RUBBER COMPOSITION AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2004-12-09 WO disclosed
US-6740704-B2 UNIFORM DISPERSION JSR CORPORATION (JP) 2004-05-25 US disclosed
US-20040030027-A1 Diene rubber/inorganic compound composite and method for producing the same and rubber composition BRIDGESTONE CORPORATION (JP) 2004-02-12 US disclosed
EP-1323775-A1 DIENE RUBBER/INORGANIC COMPOUND COMPOSITE AND METHOD FOR PRODUCING THE SAME AND RUBBER COMPOSITION JSR Corporation (JP) 2003-07-02 EP disclosed
US-20020111418-A1 Methods for producing diene-based rubber/inorganic compound complexes and rubber compositions containing the same JSR CORPORATION (JP) 2002-08-15 US disclosed
EP-1215226-A2 Diene-based rubber/inorganic compound complexes, methods for producing the same and rubber compositions containing the same JSR Corporation (JP) 2002-06-19 EP disclosed