Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | AKT2 | P31751 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31108597 | 1.00 | SIRT2 (0.43) | SIRT2PTPN1CHRM5CHRM1CHRM3 | |
| SCHEMBL31108595 | 0.95 | SIRT2 (0.41) | SIRT2PTPN1CHRM5CHRM1CHRM3 | |
| SCHEMBL31108543 | 0.95 | SIRT2 (0.41) | SIRT2PTPN1CHRM5CHRM1CHRM3 | |
| SCHEMBL29237814 | 0.90 | SIRT2 (0.41) | SIRT2PTPN1CHRM5CHRM1CHRM3 | |
| SCHEMBL30217058 | 0.88 | SIRT2 (0.40) | SIRT2PTPN1CHRM5CHRM1CHRM3 | |
| SCHEMBL30967835 | 0.88 | SIRT2 (0.40) | SIRT2PTPN1CHRM5CHRM1CHRM3 | |
| SCHEMBL30216997 | 0.85 | SIRT2 (0.38) | SIRT2PTPN1BRD4OPRM1OPRK1 | |
| SCHEMBL29237811 | 0.85 | SIRT2 (0.38) | SIRT2PTPN1BRD4OPRM1OPRK1 | |
| SCHEMBL31108605 | 0.82 | NPSR1 (0.40) | CHRM5CHRM1CHRM3OPRM1OPRK1 | |
| SCHEMBL29237466 | 0.82 | NPSR1 (0.40) | CHRM5CHRM1CHRM3OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201919-A | Indole compounds and methods of use | 健赞公司 | 2024-06-14 | — | — | CN | disclosed |