Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30216997 | 1.00 | SIRT2 (0.38) | SIRT2EPHX2PTPN1NPC1RAB9A | |
| SCHEMBL30967961 | 0.89 | SIRT2 (0.39) | SIRT2EPHX2PTPN1RAB9AOPRM1 | |
| SCHEMBL31108597 | 0.85 | SIRT2 (0.43) | SIRT2EPHX2PTPN1LMNAOPRM1 | |
| SCHEMBL29237224 | 0.85 | SIRT2 (0.43) | SIRT2EPHX2PTPN1LMNAOPRM1 | |
| SCHEMBL31108543 | 0.83 | SIRT2 (0.41) | SIRT2PTPN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29237814 | 0.83 | SIRT2 (0.41) | SIRT2EPHX2PTPN1LMNAOPRM1 | |
| SCHEMBL31108595 | 0.83 | SIRT2 (0.41) | SIRT2PTPN1LMNAOPRM1OPRK1 | |
| SCHEMBL30967835 | 0.81 | SIRT2 (0.40) | SIRT2EPHX2PTPN1OPRM1OPRK1 | |
| SCHEMBL30217058 | 0.81 | SIRT2 (0.40) | SIRT2EPHX2PTPN1OPRM1OPRK1 | |
| SCHEMBL29237703 | 0.74 | SIRT2 (0.41) | SIRT2PTPN1RAB9ALMNAOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201919-A | Indole compounds and methods of use | 健赞公司 | 2024-06-14 | — | — | CN | disclosed |