Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29237814 | 0.83 | SIRT2 (0.41) | CYP11B1CYP11B2EPHX2PTPN1CA12 | |
| Hydrochloric Acid SCHEMBL5254248 | 0.75 | TSHR (0.43) | CYP11B1CYP11B2PTPN1TRPV1CA12 | |
| SCHEMBL29237703 | 0.73 | SIRT2 (0.41) | CYP11B1CYP11B2PTPN1CA12CA7 | |
| SCHEMBL31108597 | 0.72 | SIRT2 (0.43) | EPHX2PTPN1CA12CA7CA9 | |
| SCHEMBL29237224 | 0.72 | SIRT2 (0.43) | EPHX2PTPN1CA12CA7CA9 | |
| SCHEMBL30967835 | 0.71 | SIRT2 (0.40) | EPHX2PTPN1CA12CA7CA9 | |
| SCHEMBL30217058 | 0.71 | SIRT2 (0.40) | EPHX2PTPN1CA12CA7CA9 | |
| SCHEMBL16319065 | 0.71 | HSP90AB1 (0.51) | CYP11B1CYP11B2TRPV1CA12CA2 | |
| SCHEMBL31108543 | 0.71 | SIRT2 (0.41) | PTPN1CA12CA7CA9CA14 | |
| SCHEMBL31108595 | 0.71 | SIRT2 (0.41) | PTPN1SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201919-A | Indole compounds and methods of use | 健赞公司 | 2024-06-14 | — | — | CN | disclosed |