Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31320831 | 1.00 | TSHR (0.48) | TSHRNPSR1MEN1USP2TP53 | |
| SCHEMBL26363773 | 1.00 | TSHR (0.48) | TSHRNPSR1MEN1USP2TP53 | |
| SCHEMBL4134712 | 1.00 | TSHR (0.48) | TSHRNPSR1MEN1USP2TP53 | |
| SCHEMBL4142892 | 1.00 | TSHR (0.48) | TSHRNPSR1MEN1USP2TP53 | |
| SCHEMBL29302373 | 1.00 | TSHR (0.48) | TSHRNPSR1MEN1USP2TP53 | |
| SCHEMBL25456799 | 1.00 | TSHR (0.48) | TSHRNPSR1MEN1USP2TP53 | |
| SCHEMBL30967761 | 1.00 | TSHR (0.48) | TSHRNPSR1MEN1USP2TP53 | |
| SCHEMBL6081536 | 0.86 | MAPT (0.47) | TSHRMEN1KMT2AALDH1A1SLC6A4 | |
| SCHEMBL4773039 | 0.84 | KIF11 (0.49) | TSHRMAPTPKMHTR2AHTR2C | |
| SCHEMBL29302376 | 0.84 | MAPT (0.49) | TSHRMEN1MAPK1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201919-A | Indole compounds and methods of use | 健赞公司 | 2024-06-14 | — | — | CN | disclosed |