Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 6/20 | 0.46 |
| ▸ | FLT4 | P35916 | 8/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 8/20 | 0.44 |
| ▸ | FLT3 | P36888 | 7/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 2/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 2/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | MERTK | Q12866 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 2/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 3/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26099160 | 1.00 | KDR (0.46) | KDRFLT4PDGFRBFLT3EGFR | |
| SCHEMBL30394221 | 1.00 | KDR (0.46) | KDRFLT4PDGFRBFLT3EGFR | |
| SCHEMBL26102366 | 0.89 | KDR (0.51) | KDRFLT4PDGFRBFLT3EGFR | |
| SCHEMBL29238215 | 0.88 | KDR (0.54) | KDRFLT4PDGFRBFLT3EGFR | |
| SCHEMBL30394611 | 0.88 | KDR (0.54) | KDRFLT4PDGFRBFLT3EGFR | |
| SCHEMBL26102182 | 0.87 | KDR (0.51) | KDRFLT4PDGFRBFLT3EGFR | |
| SCHEMBL30393995 | 0.86 | AURKA (0.54) | KDRFLT4PDGFRBFLT3EGFR | |
| SCHEMBL26101719 | 0.86 | AURKA (0.54) | KDRFLT4PDGFRBFLT3EGFR | |
| SCHEMBL30394365 | 0.86 | FLT4 (0.58) | KDRFLT4PDGFRBFLT3EGFR | |
| SCHEMBL30394286 | 0.86 | FLT4 (0.58) | KDRFLT4PDGFRBFLT3EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201909-A | Quinazoline derivative compound and use thereof | 株式会社沃若诺伊 | 2024-06-14 | — | — | CN | claimed |