Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.48 |
| ▸ | FLT4 | P35916 | 7/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.48 |
| ▸ | CSF1R | P07333 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | KIT | P10721 | 3/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.47 |
| ▸ | RAF1 | P04049 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 7/20 | 0.46 |
| ▸ | BRAF | P15056 | 2/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 5/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.44 |
| ▸ | FLT1 | P17948 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.44 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30394313 | 1.00 | AURKA (0.48) | AURKAAURKBFLT4PDGFRBCSF1R | |
| SCHEMBL30891790 | 0.92 | KDR (0.46) | AURKAAURKBFLT4PDGFRBCSF1R | |
| SCHEMBL26536043 | 0.92 | KDR (0.46) | AURKAAURKBFLT4PDGFRBCSF1R | |
| SCHEMBL26102350 | 0.92 | KDR (0.46) | AURKAAURKBFLT4PDGFRBCSF1R | |
| SCHEMBL26534887 | 0.90 | AURKA (0.51) | AURKAAURKBFLT4PDGFRBCSF1R | |
| Trifluoroacetic Acid SCHEMBL30394834 | 0.90 | KIT (0.45) | AURKAAURKBFLT4PDGFRBCSF1R | |
| Trifluoroacetic Acid SCHEMBL26103038 | 0.90 | KIT (0.45) | AURKAAURKBFLT4PDGFRBCSF1R | |
| SCHEMBL26100211 | 0.88 | KDR (0.47) | FLT4PDGFRBCSF1RFLT3KIT | |
| SCHEMBL30394312 | 0.88 | KDR (0.47) | FLT4PDGFRBCSF1RFLT3KIT | |
| SCHEMBL30891758 | 0.88 | KIT (0.47) | AURKAAURKBFLT4PDGFRBCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201909-A | Quinazoline derivative compound and use thereof | 株式会社沃若诺伊 | 2024-06-14 | — | — | CN | claimed |