SCHEMBL29238292

SCHEMBL29238292

C=C1CC(c2cc(Cl)nc(C(C)(C)C)c2)(c2nncn2C)C1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 2/20 0.32
▸ CBL P22681 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25186607 0.89 CBLB (0.34) CBLBCBL
SCHEMBL31275074 0.81 CBLB (0.37) CBLBCBL
SCHEMBL25183563 0.79 CBLB (0.36) CBLB
SCHEMBL25186784 0.76 CBLB (0.36) CBLBCBL
SCHEMBL25182975 0.71 HSD11B1 (0.36) CBLBCBL
SCHEMBL25413018 0.71 CBLB (0.48) CBLBCBL
SCHEMBL25413016 0.71 CBLB (0.48) CBLBCBL
SCHEMBL31015770 0.71 CBLB (0.31) CBLB
SCHEMBL25182843 0.70 HSD11B1 (0.31) —
SCHEMBL25180071 0.70 CBLB (0.41) CBLBCBL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118201921-A Lactams as CBL-B inhibitors selective for C-CBL 基因泰克公司 2024-06-14 — — CN disclosed
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