Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.48 |
| ▸ | TYK2 | P29597 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25112377 | 0.82 | HPGD (0.53) | HPGDSMN1; SMN2KCNK3KCNK9FFAR1 | |
| SCHEMBL14482458 | 0.77 | EPHX1 (0.50) | HPGDSMN1; SMN2KCNK3KCNK9NPC1 | |
| SCHEMBL14482453 | 0.77 | EPHX1 (0.50) | HPGDSMN1; SMN2KCNK3KCNK9NPC1 | |
| SCHEMBL21993 | 0.77 | HPGD (1.00) | HPGDSMN1; SMN2KCNK3KCNK9TYK2 | |
| SCHEMBL20005592 | 0.77 | HPGD (0.53) | HPGDSMN1; SMN2KCNK3KCNK9TYK2 | |
| SCHEMBL18927701 | 0.75 | HPGD (0.51) | HPGDSMN1; SMN2KCNK3KCNK9TYK2 | |
| SCHEMBL28620430 | 0.74 | HPGD (0.58) | HPGDSMN1; SMN2KCNK3KCNK9TYK2 | |
| Iodomethane SCHEMBL20530190 | 0.74 | HPGD (0.93) | HPGDSMN1; SMN2KCNK3KCNK9TYK2 | |
| SCHEMBL17755159 | 0.73 | HPGD (0.47) | HPGDSMN1; SMN2ALDH1A1HSD17B10ERCC5 | |
| SCHEMBL29085634 | 0.73 | HPGD (0.47) | HPGDSMN1; SMN2ALDH1A1HSD17B10ERCC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201896-A | PI 3K-alpha inhibitors and methods of use thereof | 传达治疗有限公司 | 2024-06-14 | — | — | CN | disclosed |