Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19055423 | 0.80 | TGM2 (0.41) | HPGDSMN1; SMN2TGM2ALDH1A1TP53 | |
| SCHEMBL298945 | 0.77 | TGM2 (0.47) | HPGDSMN1; SMN2TGM2ALDH1A1TP53 | |
| SCHEMBL29238385 | 0.77 | HPGD (0.62) | HPGDSMN1; SMN2KCNK3KCNK9TYK2 | |
| SCHEMBL18927701 | 0.75 | HPGD (0.51) | HPGDSMN1; SMN2KCNK3KCNK9TYK2 | |
| SCHEMBL23050087 | 0.75 | TGM2 (0.34) | HPGDSMN1; SMN2TGM2ALDH1A1L3MBTL1 | |
| SCHEMBL14464349 | 0.74 | HPGD (0.40) | HPGDSMN1; SMN2ALDH1A1TP53L3MBTL1 | |
| SCHEMBL12888034 | 0.73 | NPC1 (0.53) | HPGDSMN1; SMN2TGM2ALDH1A1NPC1 | |
| SCHEMBL19987339 | 0.73 | RAPGEF4 (0.41) | SMN1; SMN2ALDH1A1TP53MAOBNPC1 | |
| SCHEMBL18941435 | 0.73 | HPGD (0.61) | HPGDSMN1; SMN2KCNK3KCNK9TYK2 | |
| SCHEMBL7595646 | 0.72 | CHRM3 (0.39) | HPGDSMN1; SMN2ALDH1A1TP53L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018057365-A1 | ALKYLATED ALKOXYDIARYLAMINE ANTIOXIDANTS | LANXESS SOLUTIONS US INC. (US) | 2018-03-29 | — | — | WO | disclosed |