Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4881733 | 0.86 | KMT2A (0.47) | KMT2AMEN1CYP1A2PIM1HPGD | |
| SCHEMBL30624764 | 0.81 | PNMT (0.43) | KMT2AMEN1PIM1PIM2RAB9A | |
| SCHEMBL26187508 | 0.81 | PNMT (0.43) | KMT2AMEN1PIM1PIM2RAB9A | |
| SCHEMBL26187260 | 0.81 | PNMT (0.43) | KMT2AMEN1PIM1PIM2RAB9A | |
| SCHEMBL23850346 | 0.80 | PNMT (0.43) | CYP1A2PIM1HPGDPIM2 | |
| SCHEMBL23830703 | 0.80 | PNMT (0.43) | CYP1A2PIM1HPGDPIM2 | |
| SCHEMBL8356328 | 0.77 | CYP1A2 (0.52) | KMT2AMEN1CYP1A2PIM1HPGD | |
| SCHEMBL20304900 | 0.74 | PIM1 (0.52) | KMT2AMEN1PIM1RAB9AMAPT | |
| SCHEMBL22112204 | 0.74 | PNMT (0.34) | — | |
| SCHEMBL17684483 | 0.73 | CYP1A2 (0.53) | KMT2AMEN1CYP1A2PIM1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118043316-A | Factor XIIa inhibitors | 卢纳克治疗有限公司 | 2024-05-14 | — | — | CN | disclosed |