Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | PREP | P48147 | 4/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27190405 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9APREPACE2 | |
| SCHEMBL27190317 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9APREPACE2 | |
| SCHEMBL31097159 | 0.91 | PREP (0.48) | SMN1; SMN2NPC1RAB9APREPACE2 | |
| SCHEMBL9132544 | 0.89 | NPC1 (0.54) | SMN1; SMN2NPC1RAB9APREPACE2 | |
| SCHEMBL31097140 | 0.89 | PREP (0.48) | SMN1; SMN2NPC1RAB9APREPACE2 | |
| SCHEMBL31097194 | 0.88 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9APREPACE2 | |
| SCHEMBL31097167 | 0.88 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9APREPACE2 | |
| SCHEMBL31097172 | 0.87 | AGTR2 (0.51) | SMN1; SMN2NPC1RAB9APREPACE2 | |
| SCHEMBL30036922 | 0.86 | PREP (0.48) | PREPACE2 | |
| SCHEMBL27190350 | 0.86 | PREP (0.46) | SMN1; SMN2NPC1RAB9APREPACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118043316-A | Factor XIIa inhibitors | 卢纳克治疗有限公司 | 2024-05-14 | — | — | CN | disclosed |