Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853466 | 0.91 | ALDH1A1 (0.30) | ALDH1A1LMNAALOX12SMN1; SMN2 | |
| SCHEMBL16757206 | 0.69 | CHRM2 (0.30) | — | |
| SCHEMBL30962484 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL9853544 | 0.65 | — | — | |
| SCHEMBL16757111 | 0.64 | — | — | |
| SCHEMBL16757169 | 0.64 | — | — | |
| SCHEMBL16757171 | 0.64 | — | — | |
| SCHEMBL16771585 | 0.64 | — | — | |
| SCHEMBL16757110 | 0.64 | — | — | |
| SCHEMBL24630575 | 0.64 | EPHX1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591319-B | Tetrahydropyridopyrimidine derivative and application thereof | 江苏先声药业有限公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-114591319-A | Tetrahydropyridopyrimidine derivative and application thereof | 江苏先声药业有限公司 | 2022-06-07 | — | — | CN | disclosed |