SCHEMBL29241

SCHEMBL29241

CC(C)(C)c1cc(-n2nc3ccc(Cl)cc3n2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.41
RAB9A P51151 3/20 0.41
HSP90AA1 P07900 1/20 0.35
ATM Q13315 2/20 0.35
KDM4E B2RXH2 1/20 0.35
MAPT P10636 1/20 0.35
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
TSHR P16473 1/20 0.34
CYP2C19 P33261 1/20 0.34
ALOX5 P09917 4/20 0.33
PTGS2 P35354 4/20 0.33
POLB P06746 1/20 0.32
LMNA P02545 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29349567 1.00 NPC1 (0.41) NPC1RAB9AHSP90AA1ATMKDM4E
SCHEMBL23908723 0.95 NPC1 (0.38) NPC1RAB9AHSP90AA1ATMKDM4E
Bumetrizole SCHEMBL5194149 0.94 NPC1 (0.48) NPC1RAB9AHSP90AA1ATMKDM4E
Pyrrole SCHEMBL28116614 0.93 NPC1 (0.39) NPC1RAB9AHSP90AA1ATMKDM4E
Toluene SCHEMBL29114789 0.92 NPC1 (0.46) NPC1RAB9AKDM4EMAPTCYP1A2
Bumetrizole SCHEMBL8250511 0.91 NPC1 (0.54) NPC1RAB9AHSP90AA1KDM4EMAPT
SCHEMBL11668139 0.91 NPC1 (0.43) NPC1RAB9AHSP90AA1KDM4EMAPT
SCHEMBL6855338 0.90 NPC1 (0.38) NPC1RAB9AATMKDM4EMAPT
SCHEMBL22372500 0.90 NPC1 (0.44) NPC1RAB9AHSP90AA1KDM4EMAPT
SCHEMBL31419499 0.89 NPC1 (0.43) NPC1RAB9AATMKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 16988 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6391949-B1 None US claimed
US-20260146144-A1 SYNERGISTIC STABILIZER COMPOSITIONS AND METHODS FOR USING SAME FOR PROTECTING ORGANIC MATERIALS FROM UV LIGHT AND THERMAL DEGRADATION CYTEC INDUSTRIES INC. (US) 2026-05-28 US claimed
CN-122034426-A Ultraviolet-resistant anti-aging PE water pipe and preparation process thereof 安徽省华源塑业科技有限公司 2026-05-15 CN claimed
CN-122011525-A Ultraviolet-resistant rubber composite material and preparation method thereof 中国科学院长春应用化学研究所 2026-05-12 CN claimed
EP-3600224-B1 SKIN CARE COMPOSITIONS COMPRISING A TERPOLYMER, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF ISP INVESTMENTS LLC (US) 2026-05-06 EP claimed
US-12612511-B2 Flame retardant polyamide-based 3D printing extrusion materials STRATASYS, INC. (US) 2026-04-28 US claimed
US-12577374-B2 Container for, and a pack including, cyanoacrylate composition(s) HENKEL AG & CO. KGAA (DE) 2026-03-17 US claimed
US-20260071052-A1 Capsule Filled with Polymer Additives, Polymer-Additive Pods, and Methods for Using Them in a Polymer-Compounding Process DOVER CHEMICAL CORPORATION (US) 2026-03-12 US claimed
CN-121574693-A Flame-retardant sealant and preparation method thereof 杭州之江有机硅化工有限公司 2026-02-27 CN claimed
CN-121574669-A Low-auxiliary migration transparent adhesive film and preparation method thereof 宁波激智科技股份有限公司 2026-02-27 CN claimed
US-4045404-A OXIDATIVE AND THERMAL STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1977-08-30 US claimed
US-4038249-A METAL SALTS OF BENZOYLOXYBENZOATES AND COMPOSITIONS STABILIZED THEREWITH CIBA-GEIGY CORPORATION (US) 1977-07-26 US claimed
US-4001181-A ACTINIC RADIATION STABILIZERS CIBA-GEIGY CORPORATION (US) 1977-01-04 US claimed
US-4000113-A POLYOLEFINS CIBA-GEIGY CORPORATION (US) 1976-12-28 US claimed
US-3991138-A Resin composition for the formation of light-degradable mulching film for agricultural use DAICEL, LTD. (JA) 1976-11-09 US claimed
US-3984541-A WHICH IMPEDE METAMORPHOSIS STAUFFER CHEMICAL COMPANY (US) 1976-10-05 US claimed
US-3978074-A CATALYTIC HYDROGENATION UNIROYAL INC. (US) 1976-08-31 US claimed
US-3960809-A POLYMERS CIBA-GEIGY CORPORATION (US) 1976-06-01 US claimed
US-3935164-A NICKEL 3,5-DI-TERT-ALKYL 4-HYDROXYBENZOATE, AND A BENZOPHENONE OR BENZOTRIAZOLE CIBA-GEIGY CORPORATION (US) 1976-01-27 US claimed
US-3935163-A NICKEL BIS(3,5-DI-TERT-ALKYL-4-HYDROXY BENZOATE AND A BENZOPHENONE OR BENZOTRIAZOLE CIBA-GEIGY CORPORATION (US) 1976-01-27 US claimed