Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 7/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GFER | P55789 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | MPO | P05164 | 1/20 | 0.30 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27224410 | 0.91 | DHODH (0.42) | DHODHGAAALDH1A1MEN1KMT2A | |
| SCHEMBL17848807 | 0.81 | DHODH (0.47) | DHODHNR4A2 | |
| SCHEMBL13743093 | 0.70 | DHODH (0.41) | DHODHNR4A2CYP1A2 | |
| SCHEMBL1568450 | 0.68 | DHODH (0.40) | DHODHNR4A2MAPTKDM4E | |
| SCHEMBL11462679 | 0.67 | — | — | |
| SCHEMBL14439039 | 0.61 | ALDH1A1 (0.40) | DHODHGAAALDH1A1MEN1KMT2A | |
| SCHEMBL31618472 | 0.61 | DHODH (0.34) | DHODH | |
| SCHEMBL28723694 | 0.61 | KDM4E (0.42) | GAAALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL28723691 | 0.58 | KDM4E (0.44) | GAAALDH1A1MEN1KMT2ACYP3A4 | |
| Cyclopropane SCHEMBL9379772 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118234711-A | Cyclopyridazine compounds | 尼科治疗有限公司 | 2024-06-21 | — | — | CN | disclosed |