SCHEMBL29243149

SCHEMBL29243149

C[Si](C)(C)O[Si](C)(C)C(c1ccccc1)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.33
GAA P10253 1/20 0.33
KMT2A Q03164 1/20 0.33
F2 P00734 1/20 0.33
TSHR P16473 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
IDO1 P14902 3/20 0.32
TDO2 P48775 2/20 0.32
EPHX1 P07099 1/20 0.32
TAAR1 Q96RJ0 2/20 0.32
HTR2A P28223 1/20 0.32
HRH1 P35367 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11889758 0.83 ESR1 (0.33) DPP4GAAKMT2AF2TSHR
SCHEMBL3286251 0.81 ESR1 (0.32) DPP4GAAKMT2AF2TSHR
SCHEMBL17520022 0.80 TAAR1 (0.35) GAAIDO1TDO2TAAR1LMNA
SCHEMBL8846140 0.78 ALDH1A1 (0.36) KMT2ATSHRIDO1
SCHEMBL15757771 0.77 ALDH1A1 (0.35) DPP4GAAKMT2AF2TSHR
SCHEMBL20235890 0.72 KMT2A (0.34) GAAKMT2ATSHRHTR2ALMNA
SCHEMBL8463740 0.72 DPP4 (0.41) DPP4GAAF2TSHRSLC6A2
SCHEMBL7063054 0.71 TAAR1 (0.32) GAAIDO1TDO2TAAR1LMNA
SCHEMBL8849269 0.70 KMT2A (0.39) DPP4GAAKMT2AF2TSHR
SCHEMBL5013270 0.70 SRC (0.44) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116634990-A Compositions comprising one or more (bio) -alkanediols with active ingredients 西姆莱斯股份公司 2023-08-22 CN disclosed