SCHEMBL29243240

SCHEMBL29243240

COC(=O)c1ccc(F)cc1S(C)(=O)=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CA9 Q16790 2/20 0.46
CA5A P35218 1/20 0.46
KDM4E B2RXH2 3/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
HSD17B10 Q99714 2/20 0.45
SLC6A4 P31645 1/20 0.44
SLC6A3 Q01959 1/20 0.44
NPC1 O15118 1/20 0.43
CASP3 P42574 1/20 0.43
RAB9A P51151 1/20 0.43
SENP8 Q96LD8 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
SENP6 Q9GZR1 1/20 0.43
VCAM1 P19320 1/20 0.42
CMA1 P23946 1/20 0.42
CA12 O43570 1/20 0.42
CA7 P43166 1/20 0.42
PDK2 Q15119 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1110811 0.87 CDK1 (0.48) CA1CA2CA9CA5AKDM4E
SCHEMBL22827958 0.85 CA1 (0.45) CA1CA2CA9CA5AKDM4E
SCHEMBL16904960 0.81 CA1 (0.47) CA1CA2CA9CA5AKDM4E
SCHEMBL4312860 0.81 KEAP1 (0.47) CA1CA2KDM4EHSD17B10ACLY
SCHEMBL1741588 0.80 KDM4E (0.52) CA1CA2CA9CA5AKDM4E
SCHEMBL14687567 0.80 GAA (0.60) CA1CA2CA9CA5AKDM4E
SCHEMBL1369472 0.80 NR4A2 (0.48) CA1CA2CA9CA5AKDM4E
SCHEMBL29123913 0.80 CFTR (0.61) CA1CA2CA9CA5AKDM4E
SCHEMBL15836209 0.79 KDM4E (0.51) CA1CA2CA9CA5AKDM4E
SCHEMBL2708451 0.78 SLC6A4 (0.51) CA1CA2CA9KDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112204008-B Sulfonylaminobenzamides and sulfonylaminobenzamide derivatives 奥索生物公司 2024-07-05 CN disclosed