Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 13/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 13/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 10/20 | 0.33 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24424506 | 1.00 | TLR8 (0.33) | TLR8TLR7TLR9TBK1KDM5A | |
| SCHEMBL29585034 | 1.00 | TLR8 (0.33) | TLR8TLR7TLR9TBK1KDM5A | |
| SCHEMBL29584400 | 1.00 | TLR8 (0.33) | TLR8TLR7TLR9TBK1KDM5A | |
| SCHEMBL24424507 | 1.00 | TLR8 (0.33) | TLR8TLR7TLR9TBK1KDM5A | |
| SCHEMBL29584316 | 1.00 | TLR8 (0.33) | TLR8TLR7TLR9TBK1KDM5A | |
| SCHEMBL25090954 | 0.92 | TLR8 (0.36) | TLR8TLR7TLR9TBK1KDM5A | |
| SCHEMBL29584646 | 0.92 | TLR8 (0.36) | TLR8TLR7TLR9TBK1KDM5A | |
| SCHEMBL24423698 | 0.90 | TLR8 (0.33) | TLR8TLR7TLR9TBK1KDM5A | |
| SCHEMBL24423699 | 0.90 | TLR8 (0.33) | TLR8TLR7TLR9TBK1KDM5A | |
| SCHEMBL24423697 | 0.90 | TLR8 (0.33) | TLR8TLR7TLR9TBK1KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116635380-A | PPARgamma modulators and methods of use | 卫材R&D管理有限公司 | 2023-08-22 | — | — | CN | disclosed |