SCHEMBL29244359

SCHEMBL29244359

C=CC(=O)NC(C(C)C)C(C)C

nearest known ligand 0.65

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.65
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
TAS1R3 Q7RTX0 2/20 0.40
TAS1R1 Q7RTX1 2/20 0.40
ALDH1A1 P00352 3/20 0.39
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CYP2C19 P33261 1/20 0.38
TAS1R2 Q8TE23 1/20 0.35
ACACB O00763 2/20 0.34
TGM2 P21980 3/20 0.33
GAA P10253 1/20 0.33
ZDHHC20 Q5W0Z9 1/20 0.33
ZDHHC2 Q9UIJ5 1/20 0.33
LMNA P02545 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1907642 0.80 TSHR (0.65) TSHRMEN1KMT2AALDH1A1MAPK1
Propene SCHEMBL28398865 0.80 TSHR (0.90) TSHRMEN1KMT2AALDH1A1MAPK1
SCHEMBL8643961 0.80 TSHR (0.65) TSHRTAS1R3TAS1R1ALDH1A1MAPK1
SCHEMBL27799665 0.79 TSHR (1.00) TSHRMEN1KMT2AALDH1A1MAPK1
SCHEMBL26479936 0.79 TSHR (0.71) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL636063 0.79 TSHR (0.71) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL15072 0.79
SCHEMBL3888297 0.78 TSHR (0.62) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL6882541 0.78 TSHR (0.56) TSHRMEN1KMT2AALDH1A1MAPK1
Water SCHEMBL23706522 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118047904-A Branched polyacrylamide, synthesis method and method for synthesizing stretchable and tough hydrogel by using branched polyacrylamide 河南省科学院高新技术研究中心 2024-05-17 CN disclosed